| METHOD FOR SIMULATING PLEURAL TUBERCULOSIS | |
| 2024-04-09 | |
| 专利权人 | ST PETERSBURG EMERGENCY SCI RES INST (SPET-Non-standard) |
| 申请日期 | 2024-04-09 |
| 专利号 | RU2832685-C1 |
| 成果简介 | NOVELTY - Invention refers to experimental medicine, namely to phthisiology and thoracic surgery. Immunosuppressant infliximab in dose of 10 mg/kg is introduced into a marginal ear vein in rabbits. One day later, soft tissues are incised to the pleura, after which a catheter is inserted into the pleural cavity, through which a suspension of Mycobacterium tuberculosis H37Rv strain in concentration of 106 microbial cells in 10 ml of physiological solution and 40 ml of air is introduced. USE - Medicine. ADVANTAGE - Method makes it possible to reproduce tuberculosis pleura under experimental conditions using minimally invasive surgical approach, which in turn makes it possible to carry out lifetime monitoring of development and assessment of severity of specific inflammatory process from the moment of infection to euthanasia in a specific animal included in the study. 1 cl, 6 dwg, 1 ex |
| IPC 分类号 | A61B-017/00 ; A61K-033/14 ; A61K-039/04 ; A61K-009/08 ; A61M-025/01 ; A61P-043/00 ; G09B-023/28 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/17295 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | ST PETERSBURG EMERGENCY SCI RES INST (SPET-Non-standard) |
| 推荐引用方式 GB/T 7714 | OBORNEV A D,VINOGRADOVA T I,AVETISIAN A O,et al. METHOD FOR SIMULATING PLEURAL TUBERCULOSIS. RU2832685-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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