| METHOD OF PRODUCING (E)-5-AMINO-3-HYDRAZONO-4-HYDROXY-1-(2-HYDROXYPHENYL)-6a-(1H-INDOL-3-yl)-4-PHENYLHEXAHYDROPYRROLO(3,4-b)PYRROLE-2,6-DIONE AS AGENT WITH ANTI-TUBERCULOSIS ACTIVITY | |
| 2024-04-15 | |
| 专利权人 | UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C) |
| 申请日期 | 2024-04-15 |
| 专利号 | RU2832681-C1 |
| 成果简介 | NOVELTY - Invention relates to a method of producing (E)-5-amino-3-hydrazono-4-hydroxy-1-(2-hydroxyphenyl)-6a-(1H-indol-3-yl)-4-phenylhexahydropyrrolo[3,4-b]pyrrole-2,6-dione of formula II. Method is carried out by holding at 85 °C 3-benzoyl-2-hydroxy-3a-(1H-indol-3-yl)-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,4(3aH)-dione I with hydrazine in molar ratio of 1:2 according to the scheme given below. USE - Chemistry. ADVANTAGE - Method of producing (E)-5-amino-3-hydrazono-4-hydroxy-1-(2-hydroxyphenyl)-6a-(1H-indol-3-yl)-4-phenylhexahydropyrrolo[3,4-b]pyrrole-2,6-dione of formula II, having anti-tuberculosis activity. 1 cl, 1 tbl, 1 ex |
| IPC 分类号 | A61K-031/407 ; A61P-031/06 ; C07D-487/04 |
| 国家 | 俄罗斯 |
| 专业领域 | 化学化工 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/17186 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C) |
| 推荐引用方式 GB/T 7714 | KARAVAEV D A,MASLIVETS A N,BALANDINA S I,et al. METHOD OF PRODUCING (E)-5-AMINO-3-HYDRAZONO-4-HYDROXY-1-(2-HYDROXYPHENYL)-6a-(1H-INDOL-3-yl)-4-PHENYLHEXAHYDROPYRROLO(3,4-b)PYRROLE-2,6-DIONE AS AGENT WITH ANTI-TUBERCULOSIS ACTIVITY. RU2832681-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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