| METHOD OF PRODUCING N-(2-AMINOETHYL)-3-BENZOYL-4-HYDROXY-1-(2-HYDROXYPHENYL)-2-(1H-INDOL-3-YL)-5-OXO-2,5-DIHYDRO-1H-PYRROLE-2-CARBOXAMIDE AS AGENT HAVING ANTI-TUBERCULOSIS ACTIVITY | |
| 2024-04-15 | |
| 专利权人 | UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C) |
| 申请日期 | 2024-04-15 |
| 专利号 | RU2835557-C1 |
| 成果简介 | NOVELTY - Invention relates to a method of producing N-(2-aminoethyl)-3-benzoyl-4-hydroxy-1-(2-hydroxyphenyl)-2-(1H-indol-3-yl)-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxamide of formula II by holding 3-benzoyl-2-hydroxy-3a-(1H-indol-3-yl)-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,4(3aH)-dione formula I with ethylenediamine at room temperature according to the following scheme. USE - Chemistry. ADVANTAGE - Method for synthesis of N-(2-aminoethyl)-3-benzoyl-4-hydroxy-1-(2-hydroxyphenyl)-2-(1H-indol-3-yl)-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxamide exhibiting anti-tuberculosis activity. 1 cl, 1 tbl, 1 ex |
| IPC 分类号 | A61K-031/404 ; A61P-031/06 ; C07D-227/10 |
| 国家 | 俄罗斯 |
| 专业领域 | 化学化工 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/17185 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C) |
| 推荐引用方式 GB/T 7714 | KARAVAEV D A,MASLIVETS A N,BALANDINA S I,et al. METHOD OF PRODUCING N-(2-AMINOETHYL)-3-BENZOYL-4-HYDROXY-1-(2-HYDROXYPHENYL)-2-(1H-INDOL-3-YL)-5-OXO-2,5-DIHYDRO-1H-PYRROLE-2-CARBOXAMIDE AS AGENT HAVING ANTI-TUBERCULOSIS ACTIVITY. RU2835557-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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