| METHOD FOR PREDICTING THE RISK OF DEVELOPING RESPIRATORY FAILURE IN PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA WITH UNDERLYING SARS-CoV2 INFECTION | |
| 2024-04-26 | |
| 专利权人 | UNIV SIBE MEDICAL (UYSI-Non-standard) |
| 申请日期 | 2024-04-26 |
| 专利号 | RU2830412-C1 |
| 成果简介 | NOVELTY - Invention relates to medicine, namely to pulmonology, preventive medicine, and can be used to predict the risk of developing respiratory failure in patients with community-acquired pneumonia with underlying SARS-CoV2 infection. General clinical state of the patient is determined and blood is analysed. Blood serum is analysed for activity of elastase-like and trypsin-like proteinases. Prediction of the risk of developing respiratory failure is calculated by formula (P): P=1/(1+e-H), where e=2.718. H is calculated by the logistic regression equation: H(x1, x2, x3, x4)=-3.370+b1x1+b2x2+b3x3+b4x4, where b1=0.003; b2=0.001; b3=-1.682; b4=1.646; x1 is activity of elastase-like proteinases, nmol BANE/min⋅ml; x2 is activity of trypsin-like proteinases, nmol BAEE/min⋅ml; x3 is type 2 diabetes mellitus: absence – 0, presence – 1; x4 is nature of disease course: mild – 1, moderate – 3, severe – 4; and if P is more than 0.5, a high risk of developing respiratory failure is predicted. USE - Medicine. ADVANTAGE - Method provides the possibility of increasing the information value of the prediction of the risk of developing respiratory failure in the patients with community-acquired pneumonia with SARS-CoV2 infection by studying biologically active molecules – determining the activity of elastase-like and trypsin-like proteinases in blood serum, as well as the nature of the clinical course of the disease and the presence of type 2 diabetes mellitus. 1 cl, 7 dwg, 3 ex |
| IPC 分类号 | A61B-005/0205 ; G01N-033/68 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/16974 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | UNIV SIBE MEDICAL (UYSI-Non-standard) |
| 推荐引用方式 GB/T 7714 | DYAKOV D A,AKBASHEVA O E,SPIRINA L V,et al. METHOD FOR PREDICTING THE RISK OF DEVELOPING RESPIRATORY FAILURE IN PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA WITH UNDERLYING SARS-CoV2 INFECTION. RU2830412-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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