VIRUS-LIKE PARTICLE VACCINE (VLP) FOR COVID-19 PREVENTION FOR PARENTERAL USE
	GREBENNIKOVA T V; SAVOCHKINA T E; CHERNORYZH I I; ELISEEVA O V; LATYSHEV O E; LEBEDEVA V V; PLOTNIKOV A A; TSIBEZOV V; CHEREPUSHKIN S A; FILATOV I E; LARICHEV V F; FEDYAKINA I T; PRILIPOV A G; OZHMEGOVA E N; NORKINA S N; KOSTINA L V; ZAIKOVA O N; KHAMETOVA K M; BALANDINA M V; ELENA M P; LESNOVA E I; IURLOV K I; AKANINA D S; KOZLOVA A A; BARANETS M S; LOSICH M A; KIRILLOV I M; GINTSBURG A L
	2024-04-27
专利权人	FEDERAL STATE BUDGETARY INST (FSBI-C)
申请日期	2024-04-27
专利号	RU2834060-C1
成果简介	NOVELTY - Vaccine based on virus-like particles for the prevention of COVID-19 is described, including: a mixture of recombinant virus-like particles containing S protein on the surface, variants 19A, Alpha, Delta, Omicron SARS-CoV-2 synthesized in the baculovirus expression system, - 20, 30, 40, 50, 60, 70 or 80 micrograms; potassium dihydrogen phosphate - 0.29 mg; disodium hydrophosphate - 0.30 mg; sodium chloride - 1.84 mg; potassium chloride - 0.04 mg; calcium chloride - 0.02 mg; tris(hydroxymethyl)aminomethane HCl - 0.03 mg; squalene–based adjuvant - 0.25 ml; thiomersal - 4.00 mcg; water for injection - up to 0.5 ml. Also described a method for the prevention of COVID-19, including the administration of the specified vaccine intramuscularly twice with an interval of 21 days between injections. USE - Biotechnology. ADVANTAGE - Group of inventions provides for the creation of a vaccine with immunogenicity sufficient to form an immune response against COVID-19, the ability to induce a humoral and cellular immune response, and stimulate the protective immunity of mucous membranes. 2 cl, 5 dwg, 1 tbl, 6 ex
IPC 分类号	A61K-039/215
国家	俄罗斯
专业领域	生物科学
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/16951
专题	中国科学院新疆生态与地理研究所
作者单位	FEDERAL STATE BUDGETARY INST (FSBI-C)
推荐引用方式 GB/T 7714	GREBENNIKOVA T V,SAVOCHKINA T E,CHERNORYZH I I,et al. VIRUS-LIKE PARTICLE VACCINE (VLP) FOR COVID-19 PREVENTION FOR PARENTERAL USE. RU2834060-C1[P]. 2024.

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