| ANTICANCER CONJUGATE BASED ON HUMAN SERUM ALBUMIN FOR IMAGING AND COMBINED THERAPY OF GLIOBLASTOMAS | |
| 2024-05-02 | |
| 专利权人 | NANOTECH TO LLC (NANO-Non-standard) |
| 申请日期 | 2024-05-02 |
| 专利号 | RU2835210-C1 |
| 成果简介 | NOVELTY - Present invention relates to biotechnology and can be used in medicine. Invention discloses an anticancer conjugate based on human serum albumin with structural formula HSA-Cy5-HcyCo(B9C2H11)2-MMAE or HSA-Cy5-HcyCo(B9C2H11)2-MMAF, having in its composition a contrast agent and a boron-containing agent, as well as a chemotherapeutic agent (MMAE or MMAF) attached to the HSA through a linker, which is cleaved in the lysosome of the tumour cell. USE - Biotechnology. ADVANTAGE - Invention can be used in diagnosing and treating human glioblastomas. 1 cl, 4 dwg, 1 tbl, 4 ex |
| IPC 分类号 | A61K-047/42 ; A61P-035/00 ; C07K-014/765 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/16927 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | NANOTECH TO LLC (NANO-Non-standard) |
| 推荐引用方式 GB/T 7714 | AVRAMCHUK T V,MEILI V,ZAKHAROVA O D,et al. ANTICANCER CONJUGATE BASED ON HUMAN SERUM ALBUMIN FOR IMAGING AND COMBINED THERAPY OF GLIOBLASTOMAS. RU2835210-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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