| METHOD FOR DIFFERENTIAL DIAGNOSIS OF CHRONIC HEPATITIS B AND CHRONIC HEPATITIS C IN PATIENTS WITH SEVERE FIBROSIS AND CIRRHOSIS | |
| 2024-05-28 | |
| 专利权人 | UNIV URAL FEDERAL (UYUR-C) |
| 申请日期 | 2024-05-28 |
| 专利号 | RU2835987-C1 |
| 成果简介 | NOVELTY - Invention refers to medicine, namely to hepatology, laboratory diagnostics, and can be used for differential diagnosis of chronic hepatitis B (CHB) and chronic hepatitis C (CHC) in patients with severe fibrosis and cirrhosis. Blood plasma is analysed for concentration of cytokines IL-10 in pg/ml, FGF-2 in pg/ml, IFN2α in pg/ml. Diagnosis in a patient with severe fibrosis and cirrhosis is established by comparing the obtained values with threshold values: at the first stage, the concentration of IFN2α is evaluated, value of which is less than 96.50 pg/ml requires a second stage for this patient, value greater than or equal to 96.50 pg/ml requires a third stage for this patient. At the second stage, the FGF-2 concentration is assessed; if the value is less than 57.26 pg/ml, CHB is diagnosed, and if the value is more than or equal to 57.26, CHC is diagnosed. At the third stage, the IL-10 concentration is assessed; if the value is less than 14.74 pg/ml, CHC is diagnosed; if the value is more than or equal to 14.74, CHB is diagnosed. USE - Medicine. ADVANTAGE - Method enables determining the cause of developing severe fibrosis and cirrhosis, which enables to divide patients into groups corresponding to the diagnosis of chronic hepatitis C or chronic hepatitis B, by determining three cytokines in blood plasma: IL-10, FGF-2 – fibroblast growth factor 2 and IFN2α. 1 cl, 1 dwg, 3 ex |
| IPC 分类号 | G01N-033/573 ; G01N-033/68 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/16555 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | UNIV URAL FEDERAL (UYUR-C) |
| 推荐引用方式 GB/T 7714 | BATSUNOV O K,ARSENTEVA N A,LYUBOVOVA N E,et al. METHOD FOR DIFFERENTIAL DIAGNOSIS OF CHRONIC HEPATITIS B AND CHRONIC HEPATITIS C IN PATIENTS WITH SEVERE FIBROSIS AND CIRRHOSIS. RU2835987-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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