| METHOD FOR DIAGNOSING ATHEROGENIC DISORDERS IN CHILDREN USING CIRCULATING microRNA | |
| 2024-05-30 | |
| 专利权人 | MOSC SCI & PRACTICAL CENT TUBERCULOSIS (MOSC-Non-standard) |
| 申请日期 | 2024-05-30 |
| 专利号 | RU2834937-C1 |
| 成果简介 | NOVELTY - Invention relates to biotechnology, namely to diagnostic methods allowing to diagnose development of atherogenic disorders in children by means of microRNA analysis in a blood plasma sample. Method consists in determining the coefficient diagnosing the development of atherogenic disorders, involves sampling venous blood in a test tube with an anticoagulant, centrifugation, sampling plasma, recovery of microRNAs, real-time PCR reaction with primers on certain types of microRNAs associated with development of atherogenic disorders: microRNA-let-7a, microRNA-let-7b, microRNA-21, microRNA-24, microRNA-125, microRNA-126, microRNA-145 and microRNA-222, under certain conditions, then calculating the coefficient (R), diagnosing the development of atherogenic disorders, by empirical formula (1), diagnosing the development of atherogenic disorders in accordance with the obtained numerical values, namely by the digital coefficient R: when R is below 1, this indicates the absence of atherogenic disorders, when R is higher than 1, this indicates the presence of atherogenic disorders, when R=1, this indicates a borderline state. USE - Biotechnology. ADVANTAGE - Method enables diagnosing the development of atherogenic disorders in children. 1 cl, 5 tbl, 1 ex |
| IPC 分类号 | C12Q-001/6886 ; G01N-033/49 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/16490 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | MOSC SCI & PRACTICAL CENT TUBERCULOSIS (MOSC-Non-standard) |
| 推荐引用方式 GB/T 7714 | PRITYKO A G,NEUDAKHIN E V,ABRAMOV A A,et al. METHOD FOR DIAGNOSING ATHEROGENIC DISORDERS IN CHILDREN USING CIRCULATING microRNA. RU2834937-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论