METHOD FOR SYNTHESIS OF OLIGONUCLEOTIDE LIBRARIES AND AUTOMATIC SYNTHESIS SYSTEM
2024-06-13
专利权人UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C)
申请日期2024-06-13
专利号RU2834478-C1
成果简介NOVELTY - Invention relates to devices for molecular biology, genetic engineering, medicine and biotechnology and is intended for synthesis of oligonucleotide libraries with density of up to 2500 spots/cm2 in automatic mode. System for automatic synthesis of oligonucleotides consists of a printer with a sealed chamber; control stand with a printer control unit, a syringe station and containers with reagents and a control computer with software for controlling the system. Inside the sealed chamber of the printer there is a printing carriage with connected tubes for supply of reagents and needle and piezoelectric dispensers located on the printing carriage and a survey chamber. On the table of the coordinator in the sealed chamber of the printer, there are modules for placing substrates, a stroboscopic chamber, a module for washing dispensers and a module for drying dispensers. Before synthesis of libraries, calibration is performed. Cyclic supply of reagents is performed from containers of syringe station through tubes to needle or piezoelectric dispensers. After the chemical reaction, the reagents are removed. USE - Biotechnology. ADVANTAGE - Group of inventions provides higher density of oligonucleotide arrays and increased scale of synthesis. 3 cl, 6 dwg, 1 tbl
IPC 分类号C12Q-001/68 ; C12Q-001/6806
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/16275
专题中国科学院新疆生态与地理研究所
作者单位
UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C)
推荐引用方式
GB/T 7714
LOSHCHILOV A G,RAGIMOV E R,GADIROV R M,et al. METHOD FOR SYNTHESIS OF OLIGONUCLEOTIDE LIBRARIES AND AUTOMATIC SYNTHESIS SYSTEM. RU2834478-C1[P]. 2024.
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