Topical hydrogel wound dressing for promoting wound healing through generation of electric fields and maintaining a moist, antimicrobial environment, comprises natural polymeric material composed of sodium alginate and Aloe vera, and piezoceramic NBT-ST-0.04BT microparticles
	PATTNAIK S; ROUT D; PRAHARAJ S; MOHANTY C
	2024-08-01
专利权人	KALINGA IND TECHNOLOGY INST (KALI-Non-standard)
申请日期	2024-08-01
专利号	IN202431058419-A
成果简介	NOVELTY - Topical hydrogel wound dressing comprises: natural polymeric material composed of sodium alginate and Aloe vera; and piezoceramic NBT-ST-0.04BT microparticles, which are prepared by a solid-state reaction and exhibit a piezoelectric constant (d33*) of 688 pm/V and a maximum electric field-induced strain value (Smax) of 0.424%, where the natural polymeric material further comprises 10 ml sodium alginate solution at 2%; 10 ml poly(vinyl alcohol) solution at 1.5%; 10 ml Aloe verasolution at 2.5%; 1.5 mg/ml NBT-ST-0.04BT microparticles; 10% Poly(ethylene glycol) diacrylate; and 10% glycerine. USE - Topical hydrogel wound dressing for promoting wound healing through the generation of electric fields and maintaining a moist, antimicrobial environment, and reducing bacterial growth. No biological data given. ADVANTAGE - The dressing provides a moist wound environment, does not adhere to the wound site, and protects newly formed tissue from destruction; is flexible thus allowing it to closely fit over an uneven wound surface, facilitating penetration at the wound site; exhibits strong water absorption properties, contributing to maintaining an optimal wound healing environment; absorbs moisture, and is easily applied and removed; is biocompatible, non-toxic, and environmentally friendly wound dressing that offers superior mechanical properties, such as flexibility and strong water absorption, while being easy to apply and remove from the wound site; and beneficial for wounds that are slow to heal or at high risk of infection. The NBTST-0.04BT microparticles produce a piezoelectric effect that generates an electric field at the wound site, thus facilitating improved wound healing, exhibit antimicrobial activity, contributing to the inhibition of bacterial growth at the wound site. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing the topical hydrogel wound dressing comprising: mixing sodium alginate solution, poly(vinyl alcohol) solution, and aloe vera solution; adding NBT-ST-0.04BT microparticles, Poly(ethylene glycol) diacrylate, and glycerine to the mixture; heating the mixture to 60℃ and adding 5 vol.% ammonium persulfate; keeping the mixture on a heating plate at 70℃ for 1 hour, followed by cooling to form the hydrogel.
IPC 分类号	A61K-031/715 ; A61K-036/886 ; A61K-009/70 ; A61L-015/60 ; A61L-026/00 ; A61P-017/02
国家	印度
专业领域	医药卫生
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/15579
专题	中国科学院新疆生态与地理研究所
作者单位	KALINGA IND TECHNOLOGY INST (KALI-Non-standard)
推荐引用方式 GB/T 7714	PATTNAIK S,ROUT D,PRAHARAJ S,et al. Topical hydrogel wound dressing for promoting wound healing through generation of electric fields and maintaining a moist, antimicrobial environment, comprises natural polymeric material composed of sodium alginate and Aloe vera, and piezoceramic NBT-ST-0.04BT microparticles. IN202431058419-A[P]. 2024.

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