METHOD FOR PREDICTION OF RISK OF DEVELOPING ENDOMETRIAL HYPERPLASIA IN WOMEN WITH OVERWEIGHT OR OBESITY
2024-08-09
专利权人UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C)
申请日期2024-08-09
专利号RU2834146-C1
成果简介NOVELTY - Invention relates to medicine, namely to clinical gynaecology, medical genetics and molecular diagnostics, and can be used to predict the risk of developing endometrial hyperplasia in women of Russian nationality, who are natives of the Central Black Earth Region of the Russian Federation with overweight or obesity. DNA is recovered from peripheral venous blood. Analysis of polymorphic markers rs11031002 and rs11031005 of the FSHB gene, rs117585797 of the ANO2 gene and rs148982377 of the ZNF789 gene. When detecting a combination of genotypes rs11031002-TT of the FSHB gene × rs117585797-CC of the ANO2 gene × rs11031005-TT of the FSHB gene × rs148982377-TC of the ZNF789 gene high risk of developing endometrial hyperplasia in overweight or obese women is predicted. USE - Medicine. ADVANTAGE - Method provides obtaining new criteria for assessing an increased risk of endometrial hyperplasia in women with overweight or obesity of Russian nationality, natives of the Central Black Earth region of the Russian Federation and having no relationship to each other based on data on polymorphic markers rs11031002 of the FSHB gene, rs117585797 of the ANO2 gene, rs11031005 of the FSHB gene, rs148982377 of the ZNF789 gene. 1 cl, 5 ex
IPC 分类号C12Q-001/6806 ; C12Q-001/6827 ; C12Q-001/686 ; C12Q-001/6876 ; C12Q-001/6883 ; G01N-033/58
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/15503
专题中国科学院新疆生态与地理研究所
作者单位
UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C)
推荐引用方式
GB/T 7714
CHURNOSOV V I,PONOMARENKO M S,RESHETNIKOV E A,et al. METHOD FOR PREDICTION OF RISK OF DEVELOPING ENDOMETRIAL HYPERPLASIA IN WOMEN WITH OVERWEIGHT OR OBESITY. RU2834146-C1[P]. 2024.
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