DNA SEQUENCES INTENDED FOR HUMAN AND ANIMAL VACCINATION AGAINST DEVELOPMENT OF DISEASE CAUSED BY STRAINS OF BRUCELLA
	KHODAROVICH I M; AKIMOV M G; KOVALCHUK S I; DEYEV S M; DEVRISHOV D A
	2024-08-12
专利权人	FEDERAL STATE BUDGETARY INST (FSBI-C)
申请日期	2024-08-12
专利号	RU2834627-C1
成果简介	NOVELTY - Disclosed is an expression DNA cassette containing a nucleotide sequence presented on Seq. 3, and coding 6 immunogens of pathogen Brucella melitensis, namely proteins omp31, p39, sp41, p22.9, L7-L12 and Omp16, simultaneously coding 6 proteins Brucella melitensis: omp31, p39 and sp41, 22.9-kDa protein, L7-L12 and Omp16. Disclosed is a method of producing a plasmid for protecting a host organism against the pathogen Brucella melitensis. Method comprises embedding an expression DNA cassette into a plasmid carrier vector for expression of proteins omp31, p39, sp41, p22.9, L7-L12 and Omp16 under the control of a strong eukaryotic promoter, such as an early promoter of cytomegalovirus CMV-IE, and a transcription terminator. This expression DNA cassette can be under the control of a strong eukaryotic promoter, such as an early promoter of cytomegalovirus (CMV-IE), and a terminator. Disclosed is plasmid pCMV-6antig-mini for protecting a host organism against the pathogen Brucella melitensis, obtained using said method, presented in Fig. 2. USE - Molecular biology; genetic engineering. ADVANTAGE - Invention extends the range of DNA vaccines and can be used to immunize humans and animals against the disease caused by Brucella strains. 3 cl, 2 dwg, 1 tbl, 9 ex
IPC 分类号	A61K-039/10 ; C12N-015/86
国家	俄罗斯
专业领域	生物科学
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/15481
专题	中国科学院新疆生态与地理研究所
作者单位	FEDERAL STATE BUDGETARY INST (FSBI-C)
推荐引用方式 GB/T 7714	KHODAROVICH I M,AKIMOV M G,KOVALCHUK S I,et al. DNA SEQUENCES INTENDED FOR HUMAN AND ANIMAL VACCINATION AGAINST DEVELOPMENT OF DISEASE CAUSED BY STRAINS OF BRUCELLA. RU2834627-C1[P]. 2024.

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