| METHOD FOR DIFFERENTIAL DIAGNOSIS OF OVARIAN CANCER, OVARIAN CYSTIC GROWTHS AND UTERINE CANCER | |
| 2024-08-16 | |
| 专利权人 | FEDERAL STATE BUDGETARY INST (FSBI-C) |
| 申请日期 | 2024-08-16 |
| 专利号 | RU2836527-C1 |
| 成果简介 | NOVELTY - Invention refers to medicine, namely to oncology, and can be used for differential diagnosis of ovarian cancer, ovarian cystic growths and uterine cancer. In urine determined are micro-RNA transcripts hsa-miR-33b-5p, hsa-miR-423-5p and hsa-miR-7-5p. Calculated are relative expression coefficients of micro-RNA hsa-miR-33b-5p (Khsa-miR-33b-5p) and hsa-miR-423-5p (Khsa-miR-423-5p) as ratio of relative expression hsa-miR-33b-5p and hsa-miR-423-5p relative to reference micro-RNA hsa-miR-7-5p. At values Khsa-miR-33b-5p ≤ 1.04*10-7 and Khsa-miR-423-5p ≤ 3.01*10-7, ovarian cancer is diagnosed. At values Khsa-miR-33b-5p ≥ 4.71*10-7 and Khsa-miR-423-5p ≥ 5.11*10-7, ovarian cystic growths are diagnosed. At values Khsa-miR-33b-5p ≥ 12.47*10-5 and Khsa-miR-423-5p ≤ 0.18*10-9, uterine cancer is diagnosed. If the coefficient K is between the above intervals, the obtained result is considered to be uncertain. USE - Medicine. ADVANTAGE - Method provides non-invasive diagnosis of ovarian cancer, ovarian cystic growths and uterine body cancer by determining micro-RNA transcripts in urine. 4 cl, 1 tbl, 3 ex |
| IPC 分类号 | C12Q-001/6806 ; C12Q-001/686 ; C12Q-001/6876 ; C12Q-001/6886 ; G01N-033/58 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/15433 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | FEDERAL STATE BUDGETARY INST (FSBI-C) |
| 推荐引用方式 GB/T 7714 | PORKHANOVA N V,FILIPPOV F E,KUTILIN D S,et al. METHOD FOR DIFFERENTIAL DIAGNOSIS OF OVARIAN CANCER, OVARIAN CYSTIC GROWTHS AND UTERINE CANCER. RU2836527-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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