| New isaindigotone derivative for use in pharmaceutical composition and use as multi-target ligands for Alzheimer's disease | |
| 2024-09-28 | |
| 专利权人 | DALE A V (DALE-Individual) |
| 申请日期 | 2024-09-28 |
| 专利号 | IN202421073399-A |
| 成果简介 | NOVELTY - Isaindigotone derivative (I) or its salt, solvent, and prodrug is new. USE - Isaindigotone derivative for use in pharmaceutical composition (claimed), and use as multi-target ligands for Alzheimer's disease. ADVANTAGE - The isaindigotone derivative has improved antioxidant activity, and ensures in-silico interaction with the target such as acetyl cholinesterase (AChE), butyryl cholinesterase (BChE), monoamine oxidase A (MAO-A) and monoamine oxidase A (MAO-B). DETAILED DESCRIPTION - Isaindigotone derivative of formula (I) or its salt, solvent, and prodrug is new. R=groups of formulae (i) or (ii). INDEPENDENT CLAIMS are included for: 1.a pharmaceutical composition, which comprises isaindigotone derivatives (I), and salts, solvent and prodrug, and excipient; and 2. a method for preparing (I). |
| IPC 分类号 | A61K-047/00 ; A61K-009/00 ; A61P-025/28 ; C07D-209/02 ; C07D-239/00 ; C07D-239/70 |
| 国家 | 印度 |
| 专业领域 | 医药卫生 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/15013 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | DALE A V (DALE-Individual) |
| 推荐引用方式 GB/T 7714 | JADHAV Y S,MALI A B,MUJAWAR S A,et al. New isaindigotone derivative for use in pharmaceutical composition and use as multi-target ligands for Alzheimer's disease. IN202421073399-A[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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