Preparing 3-azabicyclo[n.1.0]alkane compound comprises treating N-allyl amidoester compound with base and/or alkali metal alkoxide in presence of metal salt
	PRADHAN N; BASKARAN S
	2024-10-14
专利权人	INDIAN INST TECHNOLOGY MADRAS (IITM-C)
申请日期	2024-10-14
专利号	IN202441077632-A
成果简介	NOVELTY - Preparing 3-azabicyclo[n.1.0]alkane compound (2) comprises treating N-allyl amidoester compound (1) with base and/or alkali metal alkoxide in presence of metal salt. USE - Method for preparing 3-azabicyclo[n.1.0]alkane compound. ADVANTAGE - The method provides 3-azabicyclo[n.1.0]alkane compound with high yield and good stereoselectivity under ambient conditions, in simple manner. DETAILED DESCRIPTION - Preparing 3-azabicyclo[n.1.0]alkane compound of formula (2) comprises treating N-allyl amidoester compound of formula (1) with base and/or alkali metal alkoxide in presence of metal salt. R1=aralkyl, allyl, alkoxy arylalkyl, naphthalenyl methyl; R2=H or methyl; R3,RI3=CH, CH2, -CH2-CH2-CH=C(Me)2, CH-aryl, C-dialkyl, C-diaryl and C-alkylaryl; R2+R3=5-6 membered cycloalkene ring system; RI2=H or alkyl; RI2+RI3=5-6 membered ring system; m,n=0 or 1; R4=H, alkyl, or aryl; R5=alkyl or allyl; and R6=H, methyl, or absent. An INDEPENDENT CLAIM is included for 3-azabicyclo[n.1.0]alkane compound (2).
IPC 分类号	C07C-051/09 ; C07C-051/56 ; C07D-209/50 ; C07D-209/52
国家	印度
专业领域	医药卫生
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/14882
专题	中国科学院新疆生态与地理研究所
作者单位	INDIAN INST TECHNOLOGY MADRAS (IITM-C)
推荐引用方式 GB/T 7714	PRADHAN N,BASKARAN S. Preparing 3-azabicyclo[n.1.0]alkane compound comprises treating N-allyl amidoester compound with base and/or alkali metal alkoxide in presence of metal salt. IN202441077632-A[P]. 2024.

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