Synthesizing copper-doped cerium oxide nanoparticles used in therapeutic applications such as bacterial infection treatment and cancer therapy, involves using Acacia Concinna fruit extract as natural reducing agent and surfactant, reducing metal nitrates to form nanoparticles through sol-gel method
	MUDULI S; NAYAK N; SAHOO T R
	2024-11-13
专利权人	UNIV KALINGA IND TECHNOLOGY INST (UYKA-Non-standard)
申请日期	2024-11-13
专利号	IN202431087708-A
成果简介	NOVELTY - Synthesizing copper (Cu)-doped cerium oxide (CeO2) nanoparticles, involves using Acacia Concinnafruit extract as a natural reducing agent and surfactant, reducing metal nitrates to form Cu-doped CeO2 nanoparticles through a sol-gel method at 200°C for 2 hours, varying the dopant concentration of copper (Cu) in the range of 2 wt.%, 4 wt.%, and 6 wt.% to achieve different compositions of the Cu-doped CeO2 nanoparticles. USE - Method for synthesizing copper (Cu)-doped cerium oxide (CeO2) nanoparticles used in therapeutic applications, such as bacterial infection treatment and cancer therapy, preferably used for biomedicine, environmental remediation, and as a catalyst in various industrial. ADVANTAGE - The method has enzyme-mimicking activities, which makes it eco-friendly, non-toxic, and generates no harmful byproducts commonly associated with synthetic surfactants like benzalkonium chloride (BAC) and cetyltrimethylammonium bromide (CTAB). The Cu-doped CeO2 nanoparticles produced is characterized by enhanced redox cycling, reactive oxygen species (ROS) scavenging efficiency for biomedical applications including anticancer and antibacterial treatments. The Cu-doped CeO2 nanoparticles produced exhibit significant antibacterial and anticancer activity. The Cu-doped CeO2 nanoparticles produced are non-toxic, eco-friendly, and demonstrate superior catalytic activity compared to conventional CeO2 nanoparticles, making them suitable for both biomedical and environmental applications. The use of a plant-based extract as a reducing agent eliminates the need for toxic chemicals typically involved in nanoparticle synthesis, making the process more environmentally friendly. The green synthesis method is simple and cost-effective, reducing the need for expensive chemical reagents and complex processing. The Cu-doped CeO2 nanoparticles are nontoxic and biocompatible, making them suitable for biomedical applications such as drug delivery and cancer treatment. The copper doping enhances the catalytic activity, redox cycling, and antibacterial properties of the nanoparticles, making them more effective in biomedical and environmental applications. The method is scalable, making it suitable for industrial-scale production of Cu-doped CeO2 nanoparticles. The method provides a novel, green, and efficient method for synthesizing Cu-doped CeO2 nanoparticles with enhanced properties.
IPC 分类号	B01J-035/45 ; B82Y-030/00 ; B82Y-040/00 ; C01F-017/235
国家	印度
专业领域	医药卫生
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/14554
专题	中国科学院新疆生态与地理研究所
作者单位	UNIV KALINGA IND TECHNOLOGY INST (UYKA-Non-standard)
推荐引用方式 GB/T 7714	MUDULI S,NAYAK N,SAHOO T R. Synthesizing copper-doped cerium oxide nanoparticles used in therapeutic applications such as bacterial infection treatment and cancer therapy, involves using Acacia Concinna fruit extract as natural reducing agent and surfactant, reducing metal nitrates to form nanoparticles through sol-gel method. IN202431087708-A[P]. 2024.

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