Simultaneous quantification of aspirin and ticagrelor in sample, for determining single components in pharmaceutical dosage form and in bulk drug, comprises preparing sample using specified solvent mixture; separating components using C18 reverse-phase column; detecting and quantifying analytes
	GAUR R; JAISWAL S; BAIS N; GUPTA R; NAGAR R; JAIN S K; VENGURLEKAR S
	2024-12-22
专利权人	GAUR R (GAUR-Individual) ; JAISWAL S (JAIS-Individual) ; BAIS N (BAIS-Individual) ; GUPTA R (GUPT-Individual) ; NAGAR R (NAGA-Individual) ; JAIN S K (JAIN-Individual) ; VENGURLEKAR S (VENG-Individual)
申请日期	2024-12-22
专利号	IN202421101723-A
成果简介	NOVELTY - Simultaneous quantification of aspirin and ticagrelor in a sample, comprises: (a) preparing the sample using a specified solvent mixture; (b) separating components using a C18 reverse-phase column under optimized conditions; (c) detecting and quantifying analytes using UV detection at 230 nm or tandem mass spectrometry (MS/MS). USE - Method for simultaneous quantification of aspirin and ticagrelor in a sample, for determining single components in pharmaceutical dosage form and in bulk drug. ADVANTAGE - The method ensures high sensitivity, precision and accuracy, provides a robust, reproducible and validated approach for quality control and pharmacokinetic studies; obtain consistent, reliable and accurate data, is validated and optimized for quality control in pharmaceutical formulations and bioanalytical applications, ensuring global regulatory compliance and reliability in pharmacokinetic studies. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a gradient elution program with a flow rate of 1 mL/minute, ensuring resolution greater than 2 between aspirin and ticagrelor peaks.
IPC 分类号	A61K-009/20 ; G01N-030/02 ; G01N-030/36 ; G01N-030/74 ; G01N-030/88
国家	印度
专业领域	医药卫生
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/13892
专题	中国科学院新疆生态与地理研究所
作者单位	1.GAUR R (GAUR-Individual) 2.JAISWAL S (JAIS-Individual) 3.BAIS N (BAIS-Individual) 4.GUPTA R (GUPT-Individual) 5.NAGAR R (NAGA-Individual) 6.JAIN S K (JAIN-Individual) 7.VENGURLEKAR S (VENG-Individual)
推荐引用方式 GB/T 7714	GAUR R,JAISWAL S,BAIS N,et al. Simultaneous quantification of aspirin and ticagrelor in sample, for determining single components in pharmaceutical dosage form and in bulk drug, comprises preparing sample using specified solvent mixture; separating components using C18 reverse-phase column; detecting and quantifying analytes. IN202421101723-A[P]. 2024.

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