| Pharmaceutical formulation for antitussive, expectorant, and anti-asthmatic activities, comprises Eulophia guineensis extract as the active ingredient, where the formulation is selected from lip balm, lipstick, oral drops, and buccal patches | |
| 2024-12-30 | |
| 专利权人 | PATIL D R (PATI-Individual) ; SALVE A P (SALV-Individual) ; MHASKE G S (MHAS-Individual) ; SATKAR S S (SATK-Individual) ; SHINDE S B (SHIN-Individual) ; KADAM V D (KADA-Individual) ; RAWADE J B (RAWA-Individual) ; DEOKATE S T (DEOK-Individual) ; AROTE S R (AROT-Individual) ; MORE G S (MORE-Individual) ; GHOLVE S D (GHOL-Individual) ; GURAV M V (GURA-Individual) |
| 申请日期 | 2024-12-30 |
| 专利号 | IN202421104506-A |
| 成果简介 | NOVELTY - Pharmaceutical formulation comprises Eulophia guineensisextract as the active ingredient, where the formulation is selected from lip balm, lipstick, oral drops, and buccal patches, the lip balm comprises 50 mg Eulophia guineensisextract, 1 ml glycerine, 3 ml castor oil, 5 g beeswax, 0.2 ml propylene glycol, and vanilla essence as a flavoring agent, exhibiting a pH of 7.2 and a drug content of 72.4%; the lipstick comprises 50 g Eulophia guineensisextract, 1 ml glycerine, 3 ml castor oil, 5 g beeswax, 3 ml beetroot extract, 0.2 ml propylene glycol, and vanilla essence, exhibiting a pH of 7.4 and a drug content of 70.18%; the oral drop comprises 50 mg Eulophia guineensisextract, 3 ml glycerine, 5 ml honey, 1 ml propylene glycol, 1 g citric acid, 20 ml water, and vanilla essence, exhibiting a pH of 6.8 and a drug content of 99.24%; the buccal patch comprises 50 mg Eulophia guineensisextract, 1 g hydroxypropyl methylcellulose (HPMC), 20 mg gelatin. USE - Pharmaceutical formulation for antitussive, expectorant, and anti-asthmatic activities, used for managing respiratory conditions like cough and asthma, and exhibiting anti-inflammatory, antimicrobial, and wound-healing activities. No biological data given. ADVANTAGE - The Pharmaceutical formulation in the form of lip balm exhibits a spreadability of 8.043 cm2, indicating ease of application and uniform consistency, the oral drops have a viscosity of 360 cps, ensuring appropriate consistency for oral administration, the buccal patches have a weight variation of 33.50 ± 1.32 mg, ensuring uniformity and consistency across batches. The pharmaceutical formulation improves patient compliance through pleasant taste, odor, and texture in cost-effective manner. DETAILED DESCRIPTION - Pharmaceutical formulation comprises Eulophia guineensisextract as the active ingredient, where the formulation is selected from lip balm, lipstick, oral drops, and buccal patches, the lip balm comprises 50 mg Eulophia guineensisextract, 1 ml glycerine, 3 ml castor oil, 5 g beeswax, 0.2 ml propylene glycol, and vanilla essence as a flavoring agent, exhibiting a pH of 7.2 and a drug content of 72.4%; the lipstick comprises 50 g Eulophia guineensisextract, 1 ml glycerine, 3 ml castor oil, 5 g beeswax, 3 ml beetroot extract, 0.2 ml propylene glycol, and vanilla essence, exhibiting a pH of 7.4 and a drug content of 70.18%; the oral drop comprises 50 mg Eulophia guineensisextract, 3 ml glycerine, 5 ml honey, 1 ml propylene glycol, 1 g citric acid, 20 ml water, and vanilla essence, exhibiting a pH of 6.8 and a drug content of 99.24%; the buccal patch comprises 50 mg Eulophia guineensisextract, 1 g hydroxypropyl methylcellulose (HPMC), 20 mg gelatin, 0.1 mg sodium benzoate, 15 ml propylene glycol, 15 ml water, 50 mg sucrose, 2 ml glycerine, and vanilla essence, exhibiting a surface pH of 6.8, a thickness of 0.163 mm, and a drug content of 94.13%. An INDEPENDENT CLAIM is included for a method for preparing pharmaceutical formulation, comprising: (a) accurately weighing the ingredients as per the formulation requirements; (b) melting beeswax in a first container i.e. beaker A and heating glycerine, castor oil, and any additional extracts or excipients in a second container i.e. beaker B until a homogenous mixture is obtained; (c) heating the contents of both containers to a uniform temperature of 90℃; (d) combining the contents of beaker B with beaker A while stirring continuously to ensure uniform mixing; (e) transferring the resultant mixture into suitable containers for lip balm and lipstick formulations and allowing it to cool at room temperature; (f) for oral drops, dissolving Eulophia guineensisextract in water under heating, followed by the sequential addition of glycerine, honey, propylene glycol, citric acid, and vanilla essence with continuous stirring until a viscous solution is formed, cooling to room temperature; (g) for buccal patches, preparing a solution by mixing water and propylene glycol in a 1:1 ratio, dissolving Eulophia guineensisextract in the solution under heating, adding hydroxypropyl methylcellulose (HPMC), gelatin, sucrose, glycerine, sodium benzoate, and vanilla essence with continuous stirring until a viscous mixture is obtained, pouring the mixture into a petri plate, allowing it to cool and solidify, and cutting the solidified patch into pieces of desired dimensions. |
| IPC 分类号 | A61K-036/898 ; A61K-047/44 ; A61K-008/02 ; A61K-008/18 ; A61K-008/34 ; A61K-008/92 ; A61K-008/97 ; A61K-009/70 |
| 国家 | 印度 |
| 专业领域 | 医药卫生 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/13685 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | 1.PATIL D R (PATI-Individual) 2.SALVE A P (SALV-Individual) 3.MHASKE G S (MHAS-Individual) 4.SATKAR S S (SATK-Individual) 5.SHINDE S B (SHIN-Individual) 6.KADAM V D (KADA-Individual) 7.RAWADE J B (RAWA-Individual) 8.DEOKATE S T (DEOK-Individual) 9.AROTE S R (AROT-Individual) 10.MORE G S (MORE-Individual) 11.GHOLVE S D (GHOL-Individual) 12.GURAV M V (GURA-Individual) |
| 推荐引用方式 GB/T 7714 | PATIL D R,SALVE A P,MHASKE G S,et al. Pharmaceutical formulation for antitussive, expectorant, and anti-asthmatic activities, comprises Eulophia guineensis extract as the active ingredient, where the formulation is selected from lip balm, lipstick, oral drops, and buccal patches. IN202421104506-A[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论