Synthesizing silver nanoparticles (AgNPs) using Euphorbia cotinifolia leaf extract, having antimalarial activity against Plasmodium falciparum involves preparing an aqueous leaf extract, mixing it with a silver nitrate solution, and controlling reaction conditions for nanoparticle synthesis
	TIWARI S
	2024-12-31
专利权人	UNIV GALGOTIAS (UYGA-Non-standard)
申请日期	2024-12-31
专利号	IN202411105320-A
成果简介	NOVELTY - Synthesizing silver nanoparticles (AgNPs) using Euphorbia cotinifolialeaf extract, involves preparing an aqueous leaf extract, mixing it with a silver nitrate solution, and controlling reaction conditions for nanoparticle synthesis. USE - Method for synthesizing silver nanoparticles (AgNPs) using Euphorbia cotinifolialeaf extract, having antimalarial activity against Plasmodium falciparum. The antimalarial activity of nanoparticles was tested against Plasmodium falciparum. The result showed that nanoparticles exhibited EC50 value of 0.75 µg/mL. ADVANTAGE - The method is eco-friendly, scalable synthesis. The nanoparticle induces oxidative stress in the parasite by generating reactive oxygen species (ROS), disrupts mitochondrial activity, and impaires antioxidant enzyme functions, promotes apoptosis-like death in infected red blood cells, enhances their therapeutic efficacy.
IPC 分类号	A61K-033/38 ; A61K-036/47 ; A61K-009/51 ; A61P-033/06 ; B22F-009/24
国家	印度
专业领域	材料科学
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/13642
专题	中国科学院新疆生态与地理研究所
作者单位	UNIV GALGOTIAS (UYGA-Non-standard)
推荐引用方式 GB/T 7714	TIWARI S. Synthesizing silver nanoparticles (AgNPs) using Euphorbia cotinifolia leaf extract, having antimalarial activity against Plasmodium falciparum involves preparing an aqueous leaf extract, mixing it with a silver nitrate solution, and controlling reaction conditions for nanoparticle synthesis. IN202411105320-A[P]. 2024.

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