| Method for analyzing advanced anti-cancer drugs, involves performing impurity profiling and structural elucidation of approved anticancer therapies using liquid chromatography mass spectrometry technique | |
| 2025-03-27 | |
| 专利权人 | VISHNU PHARM EDUCATION & RES INST (VISH-Non-standard) ; SWETHA K (SWET-Individual) ; JABEEN N (JABE-Individual) ; SAIKRUPA R K (SAIK-Individual) ; SANDHYA R M (SAND-Individual) ; CHANDRA M S J (CHAN-Individual) ; YACHARAM S (YACH-Individual) ; MASKURI N (MASK-Individual) ; NALLALA A (NALL-Individual) ; BANDLA J (BAND-Individual) |
| 申请日期 | 2025-03-27 |
| 专利号 | IN202541029626-A |
| 成果简介 | NOVELTY - The method involves quantifying anticancer drugs with enhanced sensitivity and specificity using a validated high-performance liquid chromatography (HPLC) method. A liquid chromatography mass spectrometry (LCMS) technique is used for impurity profiling and structural elucidation of approved anticancer therapies. A spectroscopic method utilizes nuclear magnetic resonance (NMR) and ultraviolet (UV) visible spectroscopy for drug stability assessment. A comprehensive quality control framework integrates chemometric techniques for improved analytical performance. USE - Method for analyzing advanced anti-cancer drugs. ADVANTAGE - The method ensures reliability, reproductability, compliance with international council for harmonization (ICH) of technical requirements for medical for human use guidelines and regulatory requirements for pharmaceutical quality assurance, efficacy, safety and quality and compliance with international regulatory guidelines comprising ICH standards for medical quality control, develops and validates advanced analytical techniques for the accurate quantification and characterization of anticancer drugs, improves accuracy in detecting and quantifying anticancer drugs, sensitivity, analytical accuracy, sensitivity, specificity, and reproducibility, establishes robust methods for impurity profiling and structural elucidation of approved anticancer therapies, integrates spectroscopic techniques e.g. NMR and UV visible spectroscopy for enhanced stability and degradation analysis, reduces analytical time, implements chemometric approaches for data interpretation and enhanced analytical accuracy and provides a reliable quality control framework which is applied across different classes of anticancer drugs and a robust quality control framework integrating chemometric approaches to enhance analytical accuracy. |
| IPC 分类号 | G01N-021/359 ; G01N-030/72 ; G01N-030/88 ; G01N-033/15 ; G16H-070/20 |
| 国家 | 印度 |
| 专业领域 | 信息技术 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/13470 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | 1.VISHNU PHARM EDUCATION & RES INST (VISH-Non-standard) 2.SWETHA K (SWET-Individual) 3.JABEEN N (JABE-Individual) 4.SAIKRUPA R K (SAIK-Individual) 5.SANDHYA R M (SAND-Individual) 6.CHANDRA M S J (CHAN-Individual) 7.YACHARAM S (YACH-Individual) 8.MASKURI N (MASK-Individual) 9.NALLALA A (NALL-Individual) 10.BANDLA J (BAND-Individual) |
| 推荐引用方式 GB/T 7714 | SWETHA K,JABEEN N,SAIKRUPA R K,et al. Method for analyzing advanced anti-cancer drugs, involves performing impurity profiling and structural elucidation of approved anticancer therapies using liquid chromatography mass spectrometry technique. IN202541029626-A[P]. 2025. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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