Preparing herbal formulation for developing anticancer activity, comprises extracting fruits of Momordica charantia with ethanol to form charantia extract, extracting Momordica cymbalaria to form cymbalaria extract, extracting Senna auriculata to form auriculata extract and mixing all extracts
	JAYARAMAN S; RAJAGOPAL P; JAYAVEERAN H M; PARTHIBAN M
	2025-03-29
专利权人	MEENAKSHI AMMAL DENTAL COLLEGE & GEN HOS (MEEN-Non-standard) ; MEENAKSHI ACAD HIGHER EDUCATION & RES (MEEN-Non-standard)
申请日期	2025-03-29
专利号	IN202541031151-A
成果简介	NOVELTY - Preparing herbal formulation comprises: (a) extracting 40 g dried and powdered fruits of Momordica charantiawith 400 mL ethanol and concentrating under vacuum to form Momordica charantiaextract; (b) extracting 40 g dried and powdered fruits of Momordica cymbalariawith 400 mL ethanol and concentrating under vacuum to form Momordica cymbalariaextract; (c) extracting 20 g dried and powdered flowers of Senna auriculatawith 200 mL ethanol and concentrating under vacuum to form Senna auriculataextract; and (d) mixing Momordica charantiaextract, Momordica cymbalariaextract and Senna auriculataextract. USE - Process for preparing herbal formulation used for developing enhanced anticancer activity (claimed) for offering a potent, multi-targeted approach for managing or treating cervical cancer, inducing apoptosis due to cytotoxic effects and inhibiting or preventing metastasis. No biological data given. ADVANTAGE - The process for preparing herbal formulation shows a dose-dependent inhibition of cell proliferation, with an IC50value of 80 µg/mL, which is indicative of higher efficacy evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay (MTT assay) against HeLa cervical cancer cells for determining in vitro cytotoxicity of the combined extracts, reduces tumor cell viability, combined extracts reduces HeLa cell migration, anti-migratory effects inhibits cell motility, assessed by utilizing a scratch wound healing assay. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for an herbal formulation, which is prepared by the process.
IPC 分类号	A61K-036/185 ; A61K-036/42 ; A61K-036/482 ; A61P-035/00 ; G06Q-050/20
国家	印度
专业领域	信息技术
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/13372
专题	中国科学院新疆生态与地理研究所
作者单位	1.MEENAKSHI AMMAL DENTAL COLLEGE & GEN HOS (MEEN-Non-standard) 2.MEENAKSHI ACAD HIGHER EDUCATION & RES (MEEN-Non-standard)
推荐引用方式 GB/T 7714	JAYARAMAN S,RAJAGOPAL P,JAYAVEERAN H M,et al. Preparing herbal formulation for developing anticancer activity, comprises extracting fruits of Momordica charantia with ethanol to form charantia extract, extracting Momordica cymbalaria to form cymbalaria extract, extracting Senna auriculata to form auriculata extract and mixing all extracts. IN202541031151-A[P]. 2025.

条目包含的文件
条目无相关文件。

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。