System for screening micrornas to inhibit tumorigenesis in renal clear cell carcinoma through targeted Kdr expression regulation, comprises a data collection unit, computational analysis module, microRNA prediction module, validation module and a therapeutic recommendation module
	BABU R; MIJI T V; PRABHA K R; SRIDHAR M; BHARATHI M
	2025-04-01
专利权人	BABU R (BABU-Individual) ; MIJI T V (MIJI-Individual) ; PRABHA K R (PRAB-Individual) ; SRIDHAR M (SRID-Individual) ; BHARATHI M (BHAR-Individual)
申请日期	2025-04-01
专利号	IN202541032218-A
成果简介	NOVELTY - System (100) comprises a data collection unit (102), computational analysis module (104), microRNA (miRNA) prediction module (106), validation module (108) and a therapeutic recommendation module (110), where miRNA prediction module is configured to receive the miRNA expression data from various databases (e.g., TCGA-KIRC, UALCAN, GEPIA2, miRDB, MirDIP, miRNet v2.0, etc.), KDR expression levels in renal carcinoma samples, interaction data between miRNAs and KDR and statistical and computational validation models as inputs, process the received inputs and generate the Identification of miRNAs (such as hsa-miR-200c-3p) that effectively regulate KDR expression, Computational predictions of the impact of the miRNAs on tumor progression, insights into potential therapeutic interventions by co-administering miRNA-based therapies with existing drugs as output. USE - System for screening micrornas to inhibit tumorigenesis in renal clear cell carcinoma through targeted Kdr expression regulation. ADVANTAGE - The system comprises therapeutic recommendation module, which evaluates the feasibility of combining miRNA-based therapies with existing drugs. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for method for screening micrornas to inhibit tumorigenesis in renal clear cell carcinoma through targeted KDR expression regulation, which involves: (1) collecting KDR expression data; and (2) using computational analysis module that processes and normalizes the data, miRNA prediction module that identifies miRNAs and regulate KDR expression, validation module, that confirms the predicted miRNAs, and therapeutic recommendation module suggests potential miRNA-based therapies. DESCRIPTION OF DRAWING(S) - The drawing shows block diagram of a system for screening micrornas to inhibit tumorigenesis in renal clear cell carcinoma through targeted Kdr expression regulation. 100System 102Data collection unit 104Computational analysis module 106MicroRNA (miRNA) prediction module 108Validation module 110Therapeutic recommendation module
IPC 分类号	A61B-005/318 ; A61K-031/7105 ; C12N-015/113 ; C12Q-001/6886 ; G06F-017/18
国家	印度
专业领域	信息技术
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/13266
专题	中国科学院新疆生态与地理研究所
作者单位	1.BABU R (BABU-Individual) 2.MIJI T V (MIJI-Individual) 3.PRABHA K R (PRAB-Individual) 4.SRIDHAR M (SRID-Individual) 5.BHARATHI M (BHAR-Individual)
推荐引用方式 GB/T 7714	BABU R,MIJI T V,PRABHA K R,et al. System for screening micrornas to inhibit tumorigenesis in renal clear cell carcinoma through targeted Kdr expression regulation, comprises a data collection unit, computational analysis module, microRNA prediction module, validation module and a therapeutic recommendation module. IN202541032218-A[P]. 2025.

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