Composition useful for treating human congenital deficiency of the protein, respiratory complications, and hepatic complications, comprises alpha 1-proteinase inhibitor in aqueous solution
	REBBEOR J; MILLER C; KLOS A; ALLGAIER E; ZIMMERMAN T P; WEE K; STPETER M; GLANCY K; ZIMMERMAN T; ST PETER M; ZIMMERMANN T P; WEI K; CHARLES M; ANTHONY K; ERIC A; ZIMMERMAN THOMAS P; KEVIN E; MICHELLE S; KELLY G; JAMES R; REBBEOR D; MILLER CH; OLGEIER E; TSIMMERMAN T P; VI K; GLANSI K
	2018-08-02
专利权人	GRIFOLS WORLDWIDE OPERATIONS LTD (GRFO-C) ; GRIFOLS WORLDWIDE OPERATIONS LTD (GRFO-C) ; GRIFOLS GLOBAL OPERATION CO LTD (GRFO-C) ; GRIFOLS WORLDWIDE OPERATIONS LTD (GRFO-C) ; GRIFOLS WORLDWIDE OPERATIONS LTD (GRFO-C)
申请日期	2018-08-02
专利号	US2020038494-A1; JP2020019765-A; KR2020015409-A; CA3049584-A1; AU2019204927-A1; CN110787297-A; IN201944030110-A; BR102019014292-A2; EP3632412-A1; SG10201906599-A1; TW202019945-A; AR117626-A1; MX2019008968-A1; US11253578-B2; HK40026929-A0; IL267923-B; IL267923-A; CN110787297-B; IN490296-B; RU2813136-C1; JP2024040213-A; JP7458717-B2; TW833778-B1
成果简介	NOVELTY - Composition comprises greater than or equal to 100 mg/ml alpha 1-proteinase inhibitor (A1PI) in an aqueous solution. USE - The composition is useful for treating human congenital deficiency of the protein ( alpha -1 antitrypsin deficiency), respiratory complications including pulmonary emphysema, chronic obstructive pulmonary disease, and hepatic complications including hepatic cirrhosis. No biological data given. ADVANTAGE - The composition: reduces treatment costs and is suitable for chronic treatment; and is stable. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for preparing the composition, comprising preparing a solution of A1PI by concentrating an initial solution of A1PI by single-pass tangential flow filtration (SPTFF).
IPC 分类号	A61K-038/55 ; A61K-047/12 ; A61K-047/26 ; A61K-047/30 ; A61K-047/18 ; A61K-009/08 ; A61K-009/51 ; A61P-043/00 ; A61K-038/57 ; A61K-009/00 ; C07K-001/34 ; A61K-045/00 ; A61P-001/16 ; A61P-011/00 ; A61K-047/20 ; B01D-061/14 ; B01D-061/18 ; C07K-014/81 ; A61K-047/10 ; A61K-047/42 ; A61K-047/00 ; C12P-021/02 ; A61K-006/00 ; A61K-009/19 ; A61K-047/02
国家	俄罗斯
专业领域	医药卫生
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/13172
专题	中国科学院新疆生态与地理研究所
作者单位	1.GRIFOLS WORLDWIDE OPERATIONS LTD (GRFO-C) 2.GRIFOLS WORLDWIDE OPERATIONS LTD (GRFO-C) 3.GRIFOLS GLOBAL OPERATION CO LTD (GRFO-C) 4.GRIFOLS WORLDWIDE OPERATIONS LTD (GRFO-C) 5.GRIFOLS WORLDWIDE OPERATIONS LTD (GRFO-C)
推荐引用方式 GB/T 7714	REBBEOR J,MILLER C,KLOS A,et al. Composition useful for treating human congenital deficiency of the protein, respiratory complications, and hepatic complications, comprises alpha 1-proteinase inhibitor in aqueous solution. US2020038494-A1; JP2020019765-A; KR2020015409-A; CA3049584-A1; AU2019204927-A1; CN110787297-A; IN201944030110-A; BR102019014292-A2; EP3632412-A1; SG10201906599-A1; TW202019945-A; AR117626-A1; MX2019008968-A1; US11253578-B2; HK40026929-A0; IL267923-B; IL267923-A; CN110787297-B; IN490296-B; RU2813136-C1; JP2024040213-A; JP7458717-B2; TW833778-B1[P]. 2018.

条目包含的文件
条目无相关文件。

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。