| METHOD OF PRODUCING 2-(1-ETHYLSULPHONYL-3-(4-(7H-PYRROLO(2,3-D)PYRIMIDIN-4-YL)PYRAZOL-1-YL)AZETIDIN-3-YL)ACETONITRILE | |
| 2024-04-27 | |
| 专利权人 | BIOCHEMIST STOCK CO (BIOC-Non-standard) |
| 申请日期 | 2024-04-27 |
| 专利号 | RU2835441-C1 |
| 成果简介 | NOVELTY - Invention refers to medicine, pharmacology and chemical-pharmaceutical industry, namely to a method of producing a compound of formula (I). Method is carried out by reacting a compound of formula (II)' with an organic fluorine-containing acid in a mixture of solvents, which is a mixture of an aprotic organic solvent with water in a volume ratio of 1.0:10.0-10.0:1.0, respectively, and a mixture of bases consisting of an inorganic base selected from a group comprising hydroxides of alkali, alkali-earth metals or ammonium, or hydrates thereof, and alkylamine, in molar ratios of inorganic base to alkylamine from 1.0:0.1 to 1.0:10.0. USE - Chemistry. ADVANTAGE - Disclosed method enables to obtain a compound of formula (I) with high output and purity. 9 cl, 1 dwg, 2 tbl, 2 ex |
| IPC 分类号 | C07D-487/04 |
| 国家 | 俄罗斯 |
| 专业领域 | 化学化工 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/13109 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | BIOCHEMIST STOCK CO (BIOC-Non-standard) |
| 推荐引用方式 GB/T 7714 | WHITE P A,LOPATUKHIN E I,KOROLEV V L,et al. METHOD OF PRODUCING 2-(1-ETHYLSULPHONYL-3-(4-(7H-PYRROLO(2,3-D)PYRIMIDIN-4-YL)PYRAZOL-1-YL)AZETIDIN-3-YL)ACETONITRILE. RU2835441-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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