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Synthesizing darolutamide intermediate comprises reacting 2-chlorotoluene with acetyl chloride, reacting 1-(3-chloro-4-methylphenyl) ethan-1-one with dimethylformamide-dimethyl acetamide, cyclizing, oxidizing, followed by dehydrating 2-chloro-4-(1H-pyrazol-3-yl)benzamide
2024-07-24
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Preparing apabetalone and its polymorphs used for treating atherosclerosis, involves stirring charged dimethylacetamide, 4-(2-hydroxyethoxy)-3,5-dimethylbenzaldehyde, 2-amino-3,5-dimethoxybenzamide and p-Toluenesulfonic acid, crystallizing the DMAc solvated material in n-propanol and water
2024-04-23
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Pharmaceutical composition or a solid pharmaceutical composition for treating hyperproliferative disorder, comprises amorphous solid dispersion of enzalutamide as active agent in a mixture of hydroxypropyl methylcellulose phthalate and cellulose acetate phthalate as excipients
2023-12-06
