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Preparing tofacitinib or its salt used for rheumatoid arthritis, involves reacting pyrimidine derivative with chloroacetaldehyde in alkali metal salt of organic acid, reacting 7H-pyrrolo[2,3-d]pyrimidine derivative with acid, and converting 7H-pyrrolo[2,3-d]pyrimidine-2,4-diol to tofacitinib or salt
2023-09-08
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Preparing propranolol or its hydrochloride salt, used for treating multiple indications e.g. hypertension, by treating propranolol with reagent selected from e.g. dimethylamino hydrochloride, treating pure propranolol with hydrochloric acid, and isolating propranolol or its hydrochloride salt
2023-08-22
