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Preparing 5-bromo-4-(4-chlorothiophen-2-yl)thiazol-2-amine used for thrombocytopenia in adult patients with chronic liver disease, involves dissolving 2-amino-4-(4-chlorothiophen-2-yl)thiazole in solvent followed by adding brominating agent, isolating 5-bromo-4-(4-chlorothiophen-2-yl)thiazol-2-amine 2023-09-19