Professor Dr. Muhammad Riaz, after his MSc with Gold Medal, earned his PhD in Natural Product Chemistry from world renowned HEJ Research Institute of Chemistry, Karachi. During his PhD he was fortunate to discover novel bis‐ and tris‐coumarin glycosides. Right after, during his 2 years post‐ doctorate from University of Paderborn, Germany, he learnt and accomplished the total synthesis of unique, challenging and potent natural products, Xyloketals series and Mumbaistatin. Dr. Riaz then, pursued his thrust to learn medicinal chemistry and had 6 years learning, training, experience of medicinal chemistry from Virginia Commonwealth University (VCU), USA as postdoctoral fellow, research assistant professor and assistant professor (VSU). His medicinal chemistry learnings and focus include the non‐sugar anticoagulant and HSP90 modulators. Importantly, now as head of the SA‐CIRBS his prime current goal is to find and establish a most competitive and most relevant team of faculty members to ensure the founding vision of SA‐CIRBS in accordance with unmet national needs and international competitiveness.

:Organic and Medicinal Chemistry (Natural Product Chemistry, Total Synthesis and Medicinal Chemistry)

1. “Finding HSP90 Modulating Anticancer Natural Products from Daphne oleoides” HEC, (PI: M. Riaz), Rs. 4.24 million (NRPU 2019)

• G. A. Miana, M. Riaz, R. Z. Paracha, U. Z. Paracha, S. Shahzad‐ul‐Hussan(2015), Prostratin: An Overview, Mini‐Reviews in Medicinal Chemistry, 15(13), 1122‐1130. • Ayaz, M., Riaz, M., Malik, A., Ahmed, E., Lodhi M. A., Chaudhary, M. I. (2009),Elaeagnoside, Chymotrypsin Inhibiting Steroidal Glucoside from Elaeagnus orientalis. Natural Product Research, 23(5), 409‐414 • Rahman, M. A., Riaz, M., Desai, U. R. (2007),Synthesis of biologically relevant bis‐flavanoids – a review. Chemistry and Biodiversity, 4(11), 2495‐2527. • Raghuraman, A., Riaz, M., Desai, U. R. (2007),Rapid and efficient microwave‐assisted synthesis of highly sulfated organic scaffolds. Tetrahedron Letters, 48(38), 6754‐6758. • Krohn, K., Diederichs, J., Riaz, M.(2006).Synthesis of 2’‐Dealkylmumbaistatin. Tetrahedron,62(6), 1223‐1230. • Ayaz, M., Lodhi, M. A., Riaz, M., Haq, A., Malik, A., Choudhary, M. I. (2006). Novel urease inhibitors from Daphne oleoides. Journal of Enzyme Inhibition and Medicinal Chemistry, 21(5), 527‐529. • Gunnarsson G.T., Riaz, M., Adams J., Desai U.R. (2005). Synthesis of per‐sulfated flavonoids using 2,2,2‐trichloro ethyl protecting group and their factor Xa inhibition potential. Bioorganic and Medicinal Chemistry,13(5), 1783‐1789. • Dantuluri M., Gunnarsson G.T., Riaz M., Nguyen H., Desai U. R. (2005). Capillary electrophoresis of highly sulfated flavanoids and flavonoids. Analytical Biochemistry, 336(2), 316‐322. • Kolanos R., Siripurapu U., Pullagurla M., Riaz M., Setola V., Roth B. L., Dukat, M., Glennon R. A. (2005). Binding of isotryptamines and indenes at h5‐HT6 serotonin receptors,Bioorganic Medicinal Chemistry Letters,15(8), 1987‐1991. • Riaz, M., Krohn, K., Malik, A., Flörke, U. (2004).Limbetazulone, a new decahydro‐8‐oxa‐naphtho[2,1‐f]azulen‐7‐one diterpenoid, from Ballota limbeta and occurrence of two conformational isomers in the crystal. Chemistry and Biodiversity, 1(3), 458‐462. • Krohn, K., Riaz. M., Flörke, U. (2004).Synthesis of Xyloketals, Natural Products, from the Mangrove Fungus Xylaria sp. European Journal of Organic Chemistry, 2004(6), 1261‐1270. • Krohn, K., Riaz, M.(2004). Total synthesis of (+)‐Xyloketal D, a secondary metabolite from the mangrove fungus Xylaria sp. Tetrahedron Letters, 45(2), 293‐294. • Malik, A., Riaz, M., Akbar, E., Rafique, M., Afza, N. (2003). C‐Alkylated coumarin and coumarin glycoside. Heterocycles, 60, 947‐951. • Zahid, M., Ishrud, O, Pan, Y., Asim, M., Riaz, M., Ahmad, V. U. (2002). Flavonoid glycosides from Salvia moorcroftiana Wall. Carbohydrates Research, 337, 403‐407. • Riaz, M.,Krohn, K., Wray, V., Malik, A. (2002).Dicoumarinly ether glycoside from the roots of Daphne oleoides. European Journal of Organic Chemistry, 2002(8), 1436‐1438. • Mehmood, A., Malik, A., Anis, I., Khan, P. M., Riaz, M., Makhmoor, T., Chaudhary, M. I. (2002). Highly oxygenated triterpenes from the roots of Atropa acuminate. Natural Product Letters, 16(6), 371‐376. • Riaz, M., Malik, A. (2001). Novel coumarin glycosides from Daphne oleoides. Helvetica Chimica Acta, 84, 656‐661. • Riaz, M., Malik, A. (2001).Daphsaifnin, dimeric coumarin glycopyranoside from Daphne oleoides. Heterocycles,55, 769‐ 773. • Riaz, M., Malik, A., Sadhozai, S. K., Hussain, M., Ullah, N. (2001). Daphwazirin, biscoumaringlycopyranoside from Daphne oleoides. Natural Product Letters, 15, 433‐438. • Parvez, M., Riaz, M., Malik, A. (2001).Eupatorin from Otustegialimbata. Acta Crystallographica, E57, o289‐291. • Riaz, M., Malik, A. (2001). Structure determination of Daphjamilin, new bicoumarin glycoside, by NMR studies. Magnetic Resonance in Chemistry, 39, 641‐642. • Akbar. E.,Riaz, M., Malik, A. (2001). Ursene type nortriterpene from Debregessiasalsifolia. Fitotrapia,72, 382‐385. • Riaz, M., Ullah, N., Rabnawaz, H., Mehmood, A., Malik, A., A